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Endocrine Abstracts

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ea0073aep790 | Late Breaking | ECE2021

Patients susceptible to an adrenal crisis show marked differences in urinary cortisol excretion and glucocorticoid sensitive pathways

Vulto Annet , van Faassen Martijn , Kerstens Michiel , van Beek Andre

BackgroundAdrenal crisis (AC) is a life threatening medical situation caused by an absolute or relative cortisol deficiency. A biological predisposition may be of importance, because some patients never experience an AC, whereas others are admitted repeatedly to the hospital for an AC. Differences in cortisol pharmacokinetics (PK) and/or pharmacodynamics (PD) may underlie this vulnerability.ObjectiveTo study ...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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